4-溴甲基联苯作为重要中间体，广泛应用于医药、农药等领域，其合成方法以4-联苯甲醇为原料，通过溴代反应制备。
医药; 农药
合成路线 1（1. 合成：2567-29-5）
产率：95%
合成条件：With carbon tetrabromide; triphenylphosphine In dichloromethane at 20℃; for 1.50 h;
实验步骤：在室温下将四溴化碳（8.99g，27.1MMOL）和三苯基膦（7.11g，27.1MMOL）加入搅拌的联苯-4-基甲醇（5.00g，27.1MMOL）的二氯甲烷（100mL）溶液中。 在室温下继续搅拌1.5小时，然后减压蒸发除去溶剂。 残留物通过硅胶柱色谱纯化（1:20乙醚：环己烷），得到标题化合物（6.37g，95％），为白色固体.1 H NMR（400MHz：CDCl 3）：7.6（4H） ，7.45（4H），7.35（1H），4.55（2H）。
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