化学合成。
化学合成
合成路线 1（1. 合成：118591-58-5）
产率：99%
合成条件：With potassium iodide In dichloromethane for 10 h;
实验步骤：乙二醇的单保护在与乌头酸反应之前，选择性地保护二醇的官能OH（即乙二醇）。 使用氧化银和烷基卤以定量产率对二醇进行单保护。单保护二醇的制备在与树枝状聚合物核（乌头酸）反应之前，二醇是单保护的。 在二氯甲烷中，在碘化钾（KI）（0.2当量）存在下，用（1.0当量）新制备的氧化银（1.5当量）和对甲苯磺酰氯（pTSCl）（1.1当量）处理保护二醇。 将所得混合物搅拌8-10小时，得到单甲苯磺酰基保护的二醇，产率为97-99％。
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