作为医药中间体或原料药使用,具体用途未在提供的资料中详细说明。
医药
合成路线 1(1. 合成:74852-81-6)
产率:99%
合成条件:With hydrogen In ethanol at 25℃;
实验步骤:将中间体27(13.9g,68mmol)溶解在乙醇中至终浓度为0.05M。 使溶液以2mL / min,25℃和全部氢气通过钯碳催化剂筒(使用来自ThalesNano的η-立方反应器),得到标题化合物(11.69g,99%),为灰白色 固体。 5η(DMSOd6)7.08(1η,s),7.01(2η,d,J8.5Hz),6.82(1H,s),6.63(2H,d,J8.5Hz),5.35(2H,s),2.51 (3H,s)。 LCMS(ES +)174.0(M + H +)。
参考文献:
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