化学合成。
化学合成
合成路线 1（1. 合成：3480-11-3）
产率：56%
合成条件：With N-Bromosuccinimide In DMF (N,N-dimethyl-formamide) at 0℃;
实验步骤：将3g（18mmol）的2'-联噻吩和50mL的DMF置于250mL的2颈圆底烧瓶中并搅拌。 在冰浴中向混合物中滴加3.2g（18mmol）N-溴代琥珀酰亚胺（NBS）在10mL DMF中的溶液。 反应完成后，用二氯甲烷萃取反应产物，用甲醇（MeOH）重结晶，得到2.5g浅黄色固体化合物，产率为56％。 该中间体（1）通过NMR鉴定。 结果如下。 1HNMR（CDCl3 400MHz）：δ= 6.91（1H，d），6.96（1H，d），7.00（1H，dd），7.22（1H）
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