205393-22-2 保特佐米蒎烷二醇酯

名称和标识

中文名: 保特佐米蒎烷二醇酯
英文名: Bortezomib pinanediol ester
CAS号: 205393-22-2
分子式: C29H39BN4O4
分子量: 518.46
中文别名: 硼替佐米蒎烷二醇杂质; 硼替佐米二醇酯; 硼替佐米杂质5-2; 硼替佐米杂质I; 硼替佐米蒎烷二醇酯
英文别名: BORTEZOMIB-PINANEDIOL; N-[(1S)-2-[[(1R)-1-[(3aS,4S,6S,7aR)-Hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]amino]-2-oxo-1-(phenylmethyl)ethyl]-2-pyrazinecarboxamide; Bortezomib intermediates III; (1S,2S,3R,5S)-Pinanediol N-(2-pyrazinecarbony1)-L-phenylalanine-L-leucine boronate; Bortezomib impurity 4; (1R)-(1S,2S,3R,5S)-Pinanediol-N-(N-pyrazinylphenylalaninoyl)-1-amino-3-methyl-butane-1-boronate; BortezoMib InterMediate III; BortezoMib VI; N-{(1R)-3-Methyl-1-[(1S,2S,6R,8S)-2,9,9-trimethyl-3,5-dioxa-4-boratricyclo[6.1.1.0]dec-4-yl]butyl}-Nα-(2-pyrazinylcarbonyl)-L-phenylalaninamide

用途与制备

概述保特佐米蒎烷二醇酯是一种蛋白酶体抑制剂，也是 Bortezomib (HY-10227) 的前体药。Bortezomib-pinanediol 抑制细胞生长，可用于多发性骨髓瘤的研究。

医药

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