生命科学，是高效的选择性IRE1 Rnase抑制剂。
医药
合成路线 1（1. 合成：14003-96-4）
产率：45%
合成条件：Stage #1: at 70 - 80℃; for 6 h; Stage #2: for 0.67 h; Heating
实验步骤：根据文献制备8-甲酰基-7-羟基-4-甲基香豆素.7-羟基-4-甲基香豆素（10g，56.8mmol）和六胺（19.9g，142mmol）的冰醋酸（90mL）加热 在70-80℃下保持6小时。 然后加入20％HCl（130mL）并将混合物进一步加热40分钟。 然后冷却混合物并用乙醚萃取两次。 减压浓缩合并的有机层，得到化合物2，为浅黄色粉末。 将粗产物用甲醇重结晶（产率，45％）。 M. p。 140-142℃.1 H NMR（300MHz，CDCl 3）：δ12.24（s，1H），10.64（s，1H），7.76-7.73（d，1H），6.94-6.91（d，1H），6.23（ s，1H），2.45（s，3H）。 FT-IR（KBr，cm -1）：3050,1720,1610
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