50816-19-8 8-溴正辛醇

危险性质：非危险化学品

化学合成。

有机合成

合成路线 1（1. 合成：50816-19-8）

产率：100% 合成条件：With hydrogen bromide In water; toluene for 8 h; Reflux 实验步骤：将16g（110mmol）辛烷二醇溶解在250ml甲苯中。 加入15.5ml HBr（137mmol，1.25当量，48％水溶液）后，将反应混合物与dean-stark接收器一起回流以从反应中除去水。 8小时后，将混合物冷却至室温，用蒸馏水洗涤两次，用盐水洗涤一次。 用硫酸钠过滤并蒸发溶剂后，以定量收率得到溴化物。 在NMR光谱中，观察到残留的甲苯，其对后续步骤没有影响。 D2o-c = 1.23g / ml（点亮：1.22g / ml）13C NMR（CDC; ppm）：62.95（CH2OH），34.04（BrCH2CH2），32.78 / 32.71（BrCH2）和（CH2CH2OH），29.23 / 28.73 / 28.09 /25.65（CH2） 参考文献：

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