17659-49-3 3-羟基-8-甲基-8-氮杂二环[3.2.1]辛烷-3-基3-羟基-2-苯基丙酸酯

名称和标识

中文名: 3-羟基-8-甲基-8-氮杂二环[3.2.1]辛烷-3-基3-羟基-2-苯基丙酸酯
英文名: 6-Hydroxy-8-methyl-8-azabicyclo[3.2.1]octan-3-yl 3-hydroxy-2-phenylpropanoate
CAS号: 17659-49-3
分子式: C17H23NO4
分子量: 305.37
中文别名: Racanisodamine
英文别名: (1S)-6-Hydroxy-8-methyl-8-azabicyclo[3.2.1]oct-3-yl tropate; 6-Hydroxy-8-methyl-8-azabicyclo[3.2.1]oct-3-yl tropate; benzeneacetic acid, α-(hydroxymethyl)-, (1R)-6-hydroxy-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester; Benzeneacetic acid, α-(hydroxymethyl)-, 6-hydroxy-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester; 3-Hydroxy-2-phenyl-propionic acid 6-hydroxy-8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester; α-(hydroxymethyl)benzeneacetic acid 6-hydroxy-8-methyl-8-azabicyclo(3.2.1)oct-3-yl ester; 6-hydroxyhyoscyamine; Anisodamine

安全说明

运输方式为冰袋运输。危险性质：非危险化学品。海关编码:29399990

用途与制备

作为阻断M胆碱受体的抗胆碱能药物，具有明显外周抗胆碱作用，用于平滑肌痉挛、感染中毒性休克、脑血栓等血管性疾患、眩晕病、中心性视网膜炎等眼底疾患、突发性耳聋及三叉神经痛等神经痛，也用于有机磷农药中毒（效果不如阿托品）、睫状肌痉挛所致假性近视、迷走神经兴奋性增高所致缓慢性心律失常。

医药

天然品：从茄科植物唐古特莨菪中提取；合成品：人工合成（具体合成路线未明确提及）。