- 3-N-叔丁氧羰基-6-氧杂-3-氮杂二环[3.1.0]己烷为烃类衍生物，可用作医药合成中间体。
- 制备
3-N-叔丁氧羰基-6-氧杂-3-氮杂二环[3.1.0]己烷可由N-Boc-3-吡咯啉为反应原料，与间氯过氧苯甲酸氧化制备而得，可用于制备医药中间体3-烯丙基-4-羟基吡咯烷-1-羧酸叔丁酯。
医药
合成路线 1（1. 合成：114214-49-2）
产率：100%
合成条件：With 3-chloro-benzenecarboperoxoic acid In dichloromethane at 20℃; for 12 h;
实验步骤：在室温下向化合物1（4.0g，0.024mmol）的CH 2 Cl 2（40mL）溶液中加入m-CPBA（0.3mol），并将混合物在室温下搅拌12小时。 将混合物用Na 2 SO淬灭，用NaHCO 3洗涤并浓缩，得到化合物2（4.4g，100％）。 1 H NMR（400MHz，CDCl 3）：δppm：3.73（m，2H），3.60（m，2H），3.23（m，2H），1.37（s，9H）。
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