4-(羟甲基)环己烷羧酸甲酯在医药和农药领域有应用，具体用途需结合相关研究和专利进一步明确。
医药; 农药
路线1：硼烷-二甲基硫醚络合物还原法
- 步骤: 在-78℃下，向4-(甲氧基羰基)环己烷羧酸的无水THF溶液中，在20分钟内滴加硼烷-甲基硫醚络合物，将混合物搅拌3小时，然后使其缓慢达到室温。用水淬灭反应，并用EtOAc萃取混合物，有机相用盐水洗涤，经MgSO₄干燥并真空浓缩，得到标题化合物。
- 条件: With borane-dimethyl sulfide complex In tetrahydrofuran at -78℃; for 3.33 h; 缓慢达到室温
- 产率: 95%
- 参考文献: [1] Patent: US2012/165347, 2012, A1. Location in patent: Page/Page column 43 [2] Patent: CN105566324, 2016, A. Location in patent: Paragraph 0379; 0380; 0381; 0382 [3] Patent: WO2014/28597, 2014, A2. Location in patent: Page/Page column 54 [4] Patent: US2015/191434, 2015, A1. Location in patent: Paragraph 0295 [5] Bioorganic and Medicinal Chemistry Letters, 2009, vol. 19, # 6, p. 1564 - 1568 [6] Patent: US2014/121400, 2014, A1. Location in patent: Paragraph 0083-0086 [7] Patent: WO2017/79867, 2017, A1. Location in patent: Page/Page column 126; 127 [8] Patent: US2018/2276, 2018, A1. Location in patent: Paragraph 0127-0139 [9] Patent: US2018/22716, 2018, A1. Location in patent: Paragraph 0332 [10] Patent: US2018/312481, 2018, A1. Location in patent: Paragraph 0091-0092
路线2：浓硫酸催化酯化法
- 步骤: 向4-羟甲基环己烷羧酸的甲醇溶液中加入浓硫酸，将混合物温热至回流并搅拌2小时，冷却反应混合物并加入NH₄OH直至碱性，然后用乙酸乙酯萃取，合并的有机萃取液用饱和NaCl水溶液洗涤，经无水Na₂SO₄干燥，过滤，并在减压下浓缩，得到标题化合物。
