- BBB permeant
- No
- Bioavailability Score
- 0.55
- Brenk
- 3.0 alert
- CYP1A2 inhibitor
- No
- CYP2C19 inhibitor
- Yes
- CYP2C9 inhibitor
- Yes
- CYP2D6 inhibitor
- No
- CYP3A4 inhibitor
- Yes
- Consensus Log P o/w
- 2.92
- Egan
- 0.0
- GI absorption
- High
- Ghose
- None
- Leadlikeness
- 3.0
- Lipinski
- 0.0
- Log K p (skin permeation)
- -5.48 cm/s
- Log P o/w (MLOGP)
- 2.52
- Log P o/w (SILICOS-IT)
- 1.44
- Log P o/w (WLOGP)
- 3.69
- Log P o/w (XLOGP3)
- 4.47
- Log P o/w (iLOGP)
- 2.51
- Log S (Ali)
- -6.51
- Log S (ESOL)
- -4.64
- Log S (SILICOS-IT)
- -5.34
- Molar Refractivity
- 104.57
- Muegge
- 0.0
- Num. H-bond acceptors
- 6.0
- Num. H-bond donors
- 1.0
- Num. arom. heavy atoms
- 12
- Num. heavy atoms
- 28
- Num. rotatable bonds
- 11
- P-gp substrate
- Yes
- PAINS
- 0.0 alert
- Synthetic accessibility
- 3.49
- Veber
- 1.0
- 储存条件
- Sealed in dry,2-8°C
- 密度
- 1.239±0.06 g/cm³ (Predicted)
- 拓扑分子极性表面积
- 110.45 Ų
- 沸点
- 561.3±45.0 °C (Predicted)
- 溶解度
- 0.00879 mg/ml ; 0.0000228 mol/l
- 酸度系数(pKa)
- 10.66±0.46 (Predicted)
