化学合成；食品添加剂。
化学合成；食品添加剂；农药（抑制杂草）
合成路线 1（1. 合成：1080-12-2）
产率：88%
合成条件：With sodium hydroxide In ethanol; water at 0 - 20℃;
实验步骤：通用方法：在0-5℃下，向取代的苯甲醛（6a1-d1,6e，6f）和丙酮（10-25当量，过量）的乙醇溶液中加入20％（w / v）NaOH水溶液。 将反应混合物在环境温度下搅拌，并通过TLC监测反应进程。 当取代的苯甲醛被消耗时，在真空中除去过量的丙酮; 然后加入冷水，用3M HCl酸化所得溶液。 通过真空过滤收集作为固体出现的产物，用水洗涤并真空干燥。 通过柱色谱法纯化残余物或者从适当的溶剂系统中重结晶，得到取代的4-苯基丁-3-烯-2-酮7a1-d1,7e和7f。
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