作为医药中间体，用于药物合成（如专利WO2008/53131等文献中提及的药物研发）。
医药
合成路线 1（1. 合成：33233-67-9）
产率：97%
合成条件：Stage #1: With sodium hydrogencarbonate In tetrahydrofuran; water for 16 h; Stage #2: With hydrogenchloride; water In tetrahydrofuran
实验步骤：第1阶段 - Boc保护; 在室温下，将4-（氨基甲基）苯甲酸（10.00g，65.36mmol）与Boc 2 O（28.0g，130.72mmol）在H 2 O（100mL）和THF（100mL）中一起搅拌。 加入饱和NaHCO 3（水溶液）直至达到pH6并将反应搅拌16小时。 然后用1M HCl溶液将反应小心酸化至pH3，这导致固体沉淀出来。 将该EPO 60过滤并干燥，得到产物，为白色固体（16.1g，97％）。 m / z = 274 [M + Na] +。
参考文献：
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