76-38-0 甲氧氟烷
词条详情加载中…
词条详情加载中…
安全说明
职业暴露限值:Ceiling: 2 ppm (13.5 mg/m3) [60-minute] [*Note: REL for exposure to waste anesthetic gas.] 危险品运输编号:3271 RTECS号:KN7820000 Hazard Note:Irritant 危险等级:3 包装类别:III 海关编码:2909191800 存储类别:3- 易燃液体 毒害物质数据:76-38-0(Hazardous Substances Data) 毒性:One of the most potent of the inhalational anesthetics, having a very high blood-gas partition coefficient and low vapor pressure at room temperature. Methoxyflurane is metabolized to a great extent (about 50-70%) in the liver and, as a consequence, there may be release of high concentrations of fluoride, sufficient to exceed the threshold for renal damage. Its use for sustained anesthesia is limited because of this renal toxicity and was discontinued around 1980.
用途与制备
医药
工业上采用二氯二氟乙烷和甲醇在碱性催化剂存在下得粗醚,再经氧化、分离、中和而得。