964-21-6 O6-甲基-2'-脱氧鸟苷

名称和标识

中文名: O6-甲基-2'-脱氧鸟苷
英文名: O6-methyl-2'-deoxyguanosine
CAS号: 964-21-6
分子式: C11H15N5O4
分子量: 281.27
中文别名: (2R,3S,5R)-5-(2-氨基-6-甲基氧基-9H-嘌呤-9-基)-2-(羟甲基)四氢呋喃-3-醇; 2'-脱氧-6-O-甲基-鸟苷
英文别名: 6-O-METHYL-2'-DEOXYGUANOSINE; 2-Amino-6-methoxy-2'-deoxy-6-deaminoadenosine; 9-(2-Deoxy-β-D-ribofuranosyl)-6-methoxy-9H-purin-2-amine; (2R,3S,5R)-5-(2-amino-6-methoxypurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol; (2R,3S,5R)-5-(2-amino-6-methoxy-purin-9-yl)-2-methylol-tetrahydrofuran-3-ol; (2R,3S,5R)-5-(2-azanyl-6-methoxy-purin-9-yl)-2-(hydroxymethyl)oxolan-3-ol; 2-amino-9-(2-deoxy-β-D-erythro-pentofuranosyl)-6-methoxypurine; 2'-Deoxy-6-O-methyl-guanosine; O6-methyldeoxyguanosine; O6-methyl-2'-deoxy-guanosine; O(6)-methyl-2'-deoxyguanosine

用途与制备

概述 O6-Methyldeoxy guanosine; DNA adduct 是一种嘌呤核苷类似物。嘌呤核苷类似物具有广泛的抗肿瘤活性，靶向惰性淋巴系统恶性肿瘤。这一过程中的抗癌机制依赖于抑制 DNA 合成，诱导细胞凋亡 (apoptosis) 等。

医药

词条详情加载中…