27219-07-4 Boc-5-氨基戊酸

危险性质：非危险化学品

化学合成。

化学合成

合成路线 1（1. 合成：27219-07-4）

产率：93.5% 合成条件：With hydrogenchloride In 1,4-dioxane; sodium hydroxide 实验步骤：实施例4向含有5-氨基戊酸（5.85g，0.05mol）的100ml 2％氢氧化钠水溶液和100ml二恶烷中的溶液滴加含有二碳酸二叔丁酯（10.9g，0.05mol）的溶液。 毫升二恶烷。 将反应混合物搅拌18小时，然后用1N盐酸酸化至pH3。 将酸化的混合物用二氯甲烷萃取三次。 合并有机层，用水洗涤，用硫酸钠干燥，得到10.1g（93.5％收率）5-（叔丁氧基羰基氨基）戊酸，为白色结晶固体。 参考文献：

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