化学合成。
农药; 染料; 医药
合成路线 1（1. 合成：110964-79-9）
产率：98%
合成条件：at 140℃; for 11 h;
实验步骤：将600.00g质量分数为70％的硫酸加入到1000mL玻璃反应器中。开始自吸混合。加入97.83克99％的2-硝基-4-甲基磺酰基甲苯和1.95克98％的五氧化二钒粉末。继续搅拌10分钟。连接冷凝接收器和废气吸收装置。快速加热至140°C。开始加入68％硝酸230g。在获得氧气的同时，控制通气率为0.1克/分钟。控制滴速（0.383g / min）。大约10小时完成下降。滴加完成后，将温度保持在140℃并继续搅拌。当未反应的2-硝基-4-甲基亚磺酰基苯甲基的质量分数为1％或更低时，反应完成（从滴加完成到反应结束并经过1小时）。在搅拌下将反应溶液缓慢冷却至10至20℃。放电材料过滤器。将滤饼用水洗涤三次。每次用水150克。干燥得到2-硝基-4-甲基磺酰基苯甲酸110.20g，含量98.10％，收率：98.0％。蒸发60％硝酸205g。发烟后的硝酸配置可以反复使用。通过空气氧化吸收到硝酸钠中的吸收装置（32％氢氧化钠溶液的质量浓度）吸收少量的氮氧化物废气。
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