作为医药中间体，用于相关药物分子的合成。
医药中间体
合成路线 1（1. 合成：161157-50-2）
产率：94%
合成条件：With 3-chloro-benzenecarboperoxoic acid In dichloromethane for 16 h;
实验步骤：根据WO 97/10212，向5,6-二氢吡啶-1（2H） - 羧酸叔丁酯（2.00g，10.9mmol）的DCM溶液中加入MCPBA（4.16g，18.6mmol）并搅拌混合物。 持续16个小时。 然后用饱和焦亚硫酸钠水溶液，饱和碳酸氢钠水溶液，1N NaOH和盐水洗涤。 将有机层干燥（硫酸钠），过滤，并真空浓缩，得到7-氧杂-3-氮杂 - 双环[4.1.0]庚烷-3-羧酸叔丁酯（2.04g，94％），为油状物： 1 H NMR（400MHz，CDCl 3）δ1-45（s，9H），1。 91（m，IH），2。 04（br，IH），3。 11（m，IH），3。 21（br，IH），3。 29（m，IH），3。 45（br，IH），3。 70（br，IH），3。 88（br，IH）。
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