化学合成;生命科学,具有抗氧化、抗炎作用,能够透过细胞膜和血脑屏障,清除自由基
化学合成;生命科学
合成路线 1(1. 合成:2309-07-1)
产率:68.3%
合成条件:Reflux
实验步骤:将阿魏酸(1.94g,10mmol)在无水甲醇(3.20g,100mmol)中搅拌溶于阿魏酸溶于0.25ml浓硫酸,搅拌回流,TLC跟踪反应进程,原料点消失后,反应停止,冷却至室温后,转入冰水体系后,用10%过量的酸洗涤碳酸钠,最后的产物用饱和盐水洗涤,用乙醚萃取,分液,合并有机相,干燥用无水硫酸钠过滤,除去溶剂,粗产物用正己烷洗脱,得到标题化合物,重结晶,为白色固体,质量1.42g(理论质量2.08g),收率68.3%。
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