化学合成;材料科学。3-溴咔唑是芳基烃类受体激动剂,是环境测试和研究的标准,可用于生物活性研究、单链到四卤代咔唑的表征;作为医药中间体,亦是合成光电材料的重要中间体。
化学合成;材料科学;医药中间体;光电材料合成;芳基烃受体激动剂(环境测试和生物活性研究)
合成路线 1(N-溴代琥珀酰亚胺溴代法)
- 步骤:在室温(约25℃)下搅拌咔唑、NBS和THF,反应完成后得到中间体F,产率95%。
- 条件:With N-Bromosuccinimide In tetrahydrofuran at 25℃
- 收率:95%
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