2,4-二硝基苯基羟胺是有机合成中优良的胺化剂，可用于各类含仲氮及负碳离子化合物的胺化反应。
有机合成
路线1：
- 步骤：制备化合物1-2（2-（2,4-硝基苯氧基）异吲哚啉-1,3-二酮）17.74g（53.88mmol），将肼一水合物溶于二氯甲烷（350mL），加入反应混合物，搅拌4小时。反应完成后倒入0N搅拌的1N HCl中，过滤所得固体，用MeCN洗涤，滤液用MC和有机层萃取，得到所需化合物1-2 10.50g（98%），用MgSO₄干燥。
- 条件：With hydrazine hydrate In dichloromethane at 0℃; for 4 h;
- 产率：98%
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