化学合成;用作有机、医药中间体;制备方法包括以2-(4-硝基苯基)-2-甲基丙腈为起始物料经加氢还原反应(雷尼镍为催化剂),或以2-(4-氯苯基)-2-甲基丙腈为起始物料经氨解反应。
有机合成中间体;医药中间体
合成路线1
- 步骤:将2-(4-硝基苯基)-2-甲基丙腈还原为胺(2-3);或以2-(4-氯苯基)-2-甲基丙腈为起始物料经氨解反应制备。
- 条件:还原反应使用氯化亚锡(SnCl₂)在乙酸乙酯中回流反应2.5小时;
- 收率:95%;
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