7511-49-1 1,3,5-三(4-溴苯基)苯

该物质属于可燃固体（存储类别11），具有严重眼损伤（类别1），对水生环境有长期危害（类别4）。需避免接触眼睛，采取防护措施（P280），若接触眼睛应立即用大量水冲洗（P305+P351+P338），并注意水生环境长期保护。

1,3,5-三(4-溴苯基)苯是一种有用的研究化学品，可用作有机中间体。

实验室研发过程中；化工医药合成过程中

合成路线 1（1. 合成：7511-49-1）

• 步骤：在装有冷凝器的圆底烧瓶中，将芳基烷基酮（3mmol）和硫酸化钨酸盐（20wt％）的混合物在130℃下搅拌，通过TLC监测反应进程。芳基烷基酮消失后，继续反应2小时。冷却反应混合物，用30mL乙酸乙酯稀释并过滤以回收催化剂。将滤液用10mL水洗涤，用硫酸钠干燥并减压浓缩。残余物通过硅胶（60-120）柱色谱纯化，用（PE：EA = 9：1）作为洗脱剂，得到纯的1,3,5-芳基苯。
• 条件：With sulfated tungstate In neat (no solvent) at 130℃; for 10 h
• 产率：84%
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