14273-90-6 6-溴己酸甲酯

常温运输，非危险化学品，具有刺激性，海关编码29159000

6-溴己酸甲酯在医药和农药领域有应用，具体用途未详细说明。

医药; 农药

路线1：

• 步骤：将5.01g（25.7mmol）6-溴己酸溶于250ml甲醇中，通过剧烈鼓泡将氯化氢（气体）加入溶液2-3分钟，在15-25℃搅拌3小时，浓缩去除溶剂，得到4.84g黄色油状产物。
• 条件：氯化氢（气体）；甲醇；15-25℃搅拌3小时；浓缩。
• 收率：90%。
• 参考文献：[1] Patent: US2002/15705, 2002, A1；[5] Patent: US2012/65367, 2012, A1。

路线2：

• 步骤：向10g（50mmol）6-溴己酸的甲醇溶液中加入几滴浓H₂SO₄，回流过夜，蒸发甲醇，残余物溶于二氯甲烷，用饱和碳酸氢钠溶液洗涤，MgSO₄干燥，蒸发溶剂得到10.7g浅黄色油状产物。
• 条件：浓H₂SO₄催化；回流过夜；二氯甲烷；饱和碳酸氢钠溶液洗涤；MgSO₄干燥；蒸发溶剂。
• 收率：100%。
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