6-氨基苯酞为胺类衍生物，可用作医药化工合成中间体。具体用于制备6-氨基异苯并呋喃-1(3H)-酮（6-氨基苯酞），如将6-硝基异苯并呋喃-1(3H)-酮在甲醇中溶解，加入钯碳催化剂，在氢气气氛下搅拌过夜，抽滤、浓缩得到目标产物。
医药化工
合成路线 1（1. 合成：57319-65-0）
- 步骤：将6-硝基-1（3H）-异苯并呋喃酮（9.9g，55mmol）溶于四氢呋喃（20ml）-甲醇（60ml）混合溶剂中，加入5％钯-炭催化剂（1.5g）；在氢气氛下，室温搅拌20小时；过滤反应混合物，依次用乙酸乙酯和甲醇洗涤固体；合并滤液和洗涤液，减压浓缩；固体用乙酸乙酯洗涤，得到标题化合物（6.21g）；浓缩洗涤液，残余物用乙酸乙酯-己烷混合溶剂结晶，得到额外产物（0.95g）。
- 条件：氢气；四氢呋喃-甲醇混合溶剂；20℃；20h；5％钯-炭催化剂。
- 收率：87％。
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